LEUVEN MINDGATE

Necklace for long-term and robust cardiac monitoring in daily life


Leuven, Belgium & Eindhoven, The Netherlands - September 2, 2009 - IMEC and its research affiliate Holst Centre today present a prototype of an electrocardiogram or ECG necklace at the IEEE Engineering in Medicine & Biology Conference (EMBC) in Minneapolis, Minnesota (USA). The technology enables long-term monitoring of cardiac performance andNecklace for long-term and robust cardiac monitoring in daily life allows patients to remain ambulatory and continue their routine daily activities while under observation. The embedded beat detection algorithm copes with the artefacts inherent to ambulatory monitoring systems.

The ECG necklace is easy to use and characterized by a low power consumption ensuring 7 days autonomy. It contains IMEC's proprietary ultra-low power analog readout ASIC (application-specific integrated circuit), and relies on a low power commercial radio/microprocessor platform. A wavelet-based heart beat detection algorithm is embedded in the processor that ensures the accurate computation of the instantaneous heart rate, even under high level of noise. A second ultra-low power microcontroller unit controls the wireless transmission of the ECG data to a computer within a range of 10m. An optional memory module enables data logging for applications in which the receiving computer is not in the neighborhood.

Ambulatory cardiac monitoring systems today suffer from inaccurate measurements due to artefacts which are inherent to ambulatory situations. IMEC's embedded beat detection algorithm has been optimized for robust heart beat detection. It copes with baseline wander, EMG (electromyogram) and motion artefacts, and high and variable electrode impedance. Heart beat is detected with 1 sample resolution. The algorithm achieves best-in-class performances, with 99.8% sensitivity and 99.77% positive predictivity on both the MIT-BIH database and a proprietary database of ambulatory ECG recordings. A satisfactory performance is achieved until 0dB SNR (signal to noise ratio).

With the Human++ program, IMEC and Holst Centre aim to leverage their expertise in nanoelectronics and nanotechnology to develop solutions for a more efficient and better healthcare. IMEC's generic technology for wireless ECG systems, such as the new ECG necklace prototype, can be used for permanent screening of people at risk of cardiovascular disorders, heart beat and beat analysis information for fit & healthy people and therapy compliance and follow-up for people under cardiovascular treatment. Industry can get access to the technology by joining the Human++ program as research partner or by licensing agreements for further product development.

Caption picture: Necklace for long-term and robust cardiac monitoring in daily life

About IMEC

IMEC is a world-leading independent research center in nanoelectronics and nanotechnology. IMEC is headquartered in Leuven, Belgium, and has offices in Belgium, the Netherlands, Taiwan, US, China and Japan. Its staff of more than 1,650 people include over 550 industrial residents and guest researchers. In 2008, IMEC's revenue (P&L) was 270 million euro.
IMEC's More Moore research targets semiconductor scaling for the 22nm technology node and beyond. With its More than Moore research, IMEC invents technology for nomadic embedded systems, wireless autonomous transducer solutions, biomedical electronics, photovoltaics, organic electronics and GaN power electronics.
IMEC's research bridges the gap between the fundamental research at universities and R&D in the industry. It has unique processing and system know-how, intellectual property portfolio, state-of-the-art infrastructure, and a strong and worldwide network position. This makes IMEC a key partner for shaping the technology of the future.
Further information on IMEC can be found at www.imec.be.
IMEC is a registered trademark for the activities of IMEC International (a legal entity set up under Belgian as a 'stichting van openbaar nut'), IMEC in Belgium (IMEC vzw supported by the Flemish Government), stichting IMEC Nederland (IMEC-NL supported by the Dutch Government) and IMEC Taiwan Co. (IMEC-TW).

About Holst Centre

Holst Centre is an independent open-innovation R&D centre that develops generic technologies for Wireless Autonomous Transducer Solutions and for Systems-in-Foil. A key feature of Holst Centre is its partnership model with industry and academia around shared roadmaps and programs. It is this kind of cross-fertilization that enables Holst Centre to tune its scientific strategy to industrial needs.
Holst Centre was set up in 2005 by IMEC (Flanders, Belgium) and TNO (The Netherlands) with support from the Dutch Ministry of Economic Affairs and the Government of Flanders. It is named after Gilles Holst, a Dutch pioneer in Research and Development and first director of Philips Research.
Located on High Tech Campus Eindhoven, Holst Centre benefits from the state-of-the-art on-site facilities. Holst Centre has over 145 employees from 25 nationalities and a commitment from close to 20 industrial partners.
Visit us at www.holstcentre.com

Contact:

IMEC : Katrien Marent, Director of External Communications, T: +32 16 28 18 80, Mobile : +32 474 30 28 66, katrien.marent@imec.be

Holst Centre: Koen Snoeckx, Communication Manager, T: +31 40 277 40 91, Mobile: +31 612 719843, koen.snoeckx@holstcentre.com

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